Unexplained bruising or bleeding – Bruising easily or bleeding without an obvious cause. Unexplained weight loss – Losing weight without trying. Fatigue – Feeling very tired despite rest. Persistent pain – Unexplained pain that doesn’t go away. Changes in skin – Unexplained rashes, color changes, or moles. Lumps or bumps – Any unusual lumps or swelling under the,skin. Persistent cough or hoarseness – A cough that doesn’t go away or causes changes in voice. Difficulty swallowing – Feeling like food gets stuck in your throat. Unusual bleeding or discharge – Bleeding not related to a period, or other unexpected discharges. Changes in bowel or bladder habits – Chronic diarrhea, constipation, or blood in the stool or urine. Persistent indigestion or discomfort – Feeling bloated or nauseous for no reason. Loss of appetite – Not feeling hungry or losing interest in food. Night sweats – Excessive sweating at night.